CNPY2 is a HIF-1α-regulated, secreted angiogenic growth factor.
Guo J,et al. A secreted protein (Canopy 2, CNPY2) enhances angiogenesis and promotes smooth muscle cell migration and proliferation. Cardiovasc Res. 2015 Mar 1;105(3):383-93. doi: 10.1093/cvr/cvv010. Epub 2015 Jan 14.
Guo J, et al. Canopy 2 attenuates the transition from compensatory hypertrophy to dilated heart failure in hypertrophic cardiomyopathy. Eur Heart J. 2015 Oct 1;36(37):2530-40. doi: 10.1093/eurheartj/ehv294. Epub 2015 Jul 9.
Guo J, et al. A secreted protein (Canopy 2, CNPY2) enhances angiogenesis and promotes smooth muscle cell migration and proliferation. Cardiovasc Res. 2015 Mar 1;105(3):383-93. doi: 10.1093/cvr/cvv010.
