Monoclonal Antibody Pair High Sensitivity and Specificity
Assay Range: 19 ~ 1250 pg/mL
Sensitivity: 5 pg/mL
Calibration: recombinant human sCSF1R His Tag (HEK293)
Size: 96 T
Sample Type: Serum, plasma
Protocol or Data Sheet: SK00144-01
Macrophage Colony Stimulating Factor I Receptor (M-CSF-R)
References
The colony-stimulating factor 1 receptor (CSF1R) is a key tyrosine kinase transmembrane receptor modulating microglial homeostasis, neurogenesis, and neuronal survival in the central nervous system (CNS). CSF1R, which can be proteolytically cleaved into a soluble ectodomain and an intracellular protein fragment, supports the survival of myeloid cells upon activation by two ligands, colony stimulating factor 1 and interleukin 34. (Hu B, et al. Insights Into the Role of CSF1R in the Central Nervous System and Neurological Disorders. Front Aging Neurosci. 2021 Nov 15;13:789834.)
