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- LOX-1 is the primary receptor for oxidized low-density lipoproteins (ox-LDL) circulating in the bloodstream, originating from food intake.
- Oxidized Low-density Lipoprotein Receptor 1 (OLR1).
- LOX-1, is an inflammation-induced receptor implicated in atherosclerotic plaque formation in acute coronary syndrome.
- LOX-1 plays an important role to regulate cardiac remodeling and oxidative stress after ischemia-reperfusion.
- Endothelial cells primarily express LOX-1 as receptor for ox-LDL.
- ox-LDL has been shown to upregulate expression of LOX-1.
- Size: 96 T, 192T ($980 per 192T)
- Sensitivity at 10 pg/mL
- Monoclonal Antibody Pair Specific to the glycosylated human sLOX-1 (human cells)
- Validated by WB & E
- Calibrator: human soluble LOX-1 derived from HEK293
- Citations Available
Citations:- Gabriele, M., Pucci, L., La Marca, M. et al. Cell Mol Biol Lett 21, 10 (2016) [cell cultures samples had been tested by Aviscera Bioscience LOX-1 ELISA Kit].
- D. Kupczyk, et al, “Paraoxonase 1: The Lectin-Like Oxidized LDL Receptor Type I and Oxidative Stress in the Blood of Men with Type II Obesity,” Disease Markers, vol. 2019, Article ID 6178017, 7 pages, 2019.
- Ozkan C, et al. Proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index in patients with differentiated thyroid cancer. Endocr J. 2015;62(12):1091-9.
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Features
Size: 96 T Standard Range: 19.5 - 1250 pg/ml Sensitivity: 10 pg/ml
Specficity: human soluble LOX-1 HEK293 derived
Sample Type: serum or plasma Dilution factor: N/A Intra-CV: 4-6% Inter-CV:4-9% Data Sheet: PDF
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