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- Oxidized Low-density Lipoprotein Receptor 1 (OLR1).
- LOX-1, is an inflammation-induced receptor implicated in atherosclerotic plaque formation in acute coronary syndrome.
- LOX-1 plays an important role to regulate cardiac remodeling and oxidative stress after ischemia-reperfusion.
- Endothelial cells primarily express LOX-1 as receptor for ox-LDL.
- ox-LDL has been shown to upregulate expression of LOX-1.
- Size: 96 T
- Sensitivity at 10 pg/mL
- Monoclonal Antibody Pair Specific to the glycosylated human sLOX-1 (human cells)
- Validated by WB & E
- Calibrator: human soluble LOX-1 derived from HEK293
- Citations Available
Citations:- "A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL" by Morena Gabriele.
- D. Kupczyk, et al, “Paraoxonase 1: The Lectin-Like Oxidized LDL Receptor Type I and Oxidative Stress in the Blood of Men with Type II Obesity,” Disease Markers, vol. 2019, Article ID 6178017, 7 pages, 2019. https://doi.org/10.1155/2019/6178017.
- Ozkan C, et al. Proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index in patients with differentiated thyroid cancer. Endocr J. 2015;62(12):1091-9. doi: 10.1507/endocrj.EJ15-0308. Epub 2015 Oct 22. PMID: 26490048.
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