Angiotensin-Converting Enzyme 2 (ACE2) (Human) (HEK293)
Product Code: 00707-01-10
Our Price: $160.00
Description
$260
Feature:
- Soluble ACE2 (Human) His Tagged (HEK293) at 10 ug per vial.
- Tag: His Tag on its C-terminus
- Expression: HEK293 cells animal free culture
- Purity:> 95%
- MW: 110-120 KD (Due to Glycoylation)
- Tested by anti His Tagged Protein Monoclonal Antibody on RBD-S1 Spike Protein pre-coated microplates.
- Tested by Biotinylated RBD His Tag and Streptavidin-HRP on human ACE2 His Tag Pre-coated Microplates.
- The enzyme specific activity to cleave a fluorogenic peptide substrate, McaYVADAPK (Dnp)OH,
is >1000 pmols/min/μg. - Endotoxin<1.0 EU per μg of the protein as determined by the LAL method
- Gheblawi M., et al. Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System. Circulation Research. 2020;126:1456–1474
Features
- Protein ID: NP_068576.1
- Gene ID: NM_021804.2
- Sequence: Human ACE2 (18-740) extracellular domain.
- Tag: His Tag on its C-Terminus
- Expression: HEK293 animal free culture
- MW: 110-120 KD
- Purity: >95%
- Endotoxin:< 1.0 EU per μg protein as determined by the LAL method.
- Biological activity test: EC50= 0.235 nM/L ~1.05 nM/L Specific Binding to the recombinant S-RBD of SARS-CoV-2 (2019-nCoV) coated microplates (200ng/well)