LOX-1 (Human) Ultrasensitive ELISA Kit
Product Code: SK00006-09
Our Price: $520.00
Description
- Oxidized Low-density Lipoprotein Receptor 1 (OLR1).
- LOX-1, is an inflammation-induced receptor implicated in atherosclerotic plaque formation in acute coronary syndrome.
- LOX-1 plays an important role to regulate cardiac remodeling and oxidative stress after ischemia-reperfusion.
- Endothelial cells primarily express LOX-1 as receptor for ox-LDL.
- ox-LDL has been shown to upregulate expression of LOX-1.
- Size: 96 T
- Sensitivity at 10 pg/mL
- Monoclonal Antibody Pair Specific to the glycosylated human sLOX-1 (human cells)
- Validated by WB & E
- Calibrator: human soluble LOX-1 derived from HEK293
- Citations Available
Citations:
- "A fermented bean flour extract downregulates LOX-1, CHOP and ICAM-1 in HMEC-1 stimulated by ox-LDL" by Morena Gabriele.
- D. Kupczyk, et al, “Paraoxonase 1: The Lectin-Like Oxidized LDL Receptor Type I and Oxidative Stress in the Blood of Men with Type II Obesity,†Disease Markers, vol. 2019, Article ID 6178017, 7 pages, 2019. https://doi.org/10.1155/2019/6178017.
- Ozkan C, et al. Proprotein convertase subtilisin/kexin type 9 (PCSK9), soluble lectin-like oxidized LDL receptor 1 (sLOX-1) and ankle brachial index in patients with differentiated thyroid cancer. Endocr J. 2015;62(12):1091-9. doi: 10.1507/endocrj.EJ15-0308. Epub 2015 Oct 22. PMID: 26490048.
Features
- Size: 96 TStandard Range: 19.5 - 1250 pg/mlSensitivity: 10 pg/ml
Specficity: human soluble LOX-1 HEK293 derivedSample Type: serum or plasmaDilution factor: N/AIntra-CV: 4-6%Inter-CV:4-9%Data Sheet: PDF