Her2/ErbB2 (Soluble) (Human) ELISA Kit

Home > Research Area > Cancer Biomarkers >

Our Price: $520.00

Product Code: SK00226-06

Qty:

Description

Technical Specs

Soluble Her2/ErbB2 is a biomarker for breast cancer.

Citations:

Soluble Her2 (Human) ELISA Kit SK00226-06 had been used by Dr. Yang on follow research paper.

Lu Yang et al. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015 May; 2(5): 396–405.

ERBB2 sheds its ECD (sERBB2) via proteolytic cleavage (Codony-Servat et al., 1999). Plasma sERBB2 concentration reached ~3 ng/ml in mice bearing

CHO-K1/ERBB2 tumors but was undetectable (b5 pg/ml) in mice bearing CHO-K1 tumors (Fig. 1F). EP did not significantly alter plasma sERBB2 level, but rhPEPD reduced plasma sERBB2 by up to 68.4% (2092.0/3060.7; P=0.005, Fig. 1F), consistentwith ERBB2 depletion induced by rhPEPD in the tumor tissues.

Features

Size: 96 T
Standard Range: 46.875-3000 pg/ml
Sensitivity: 10 pg/ml
Sample Type: serum, plasma, cell cultures
Intra-CV: 4-6%
Inter-CV: 8-12%
Protocol: PDF

Browse for more products in the same category as this item:

Research Area > Cancer Biomarkers
ELISA > Human ELISA