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FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. FAP is expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas.
- Baerts L, et al. Acute Ischemic Stroke Severity, Progression, and Outcome Relate to Changes in Dipeptidyl Peptidase IV and FAP. Transl Stroke Res. 2016 Aug 26. [Epub ahead of print] PubMed PMID: 27561653.
- Tillmanns J, et al. Changes in concentrations of circulating FAP alpha are associated with myocardial damage in patients with acute ST-elevation MI. Int J Cardiol. 2017 Apr 1;232:155-159.
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