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Autotaxin/ENPP2 (Human) ELISA Kit
Human Autotaxin

Our Price: $460.00

Product Code: SK00526-06

Description Technical Specs More Information:
  • Autotaxin/ENPP2 is a biomarker for metabolic syndrome, diabetes, and liver fibrosis research.
  • Autotaxin (ATX) is a secreted lysophospholipase D involved in synthesis of lysophosphatidic acid (LPA), a phospholipid growth factor acting via specific receptors (LPA1R to LPA6R) and involved in several pathologies including obesity. ATX is secreted by adipocytes and contributes to circulating LPA. ATX expression is up-regulated in obese patients and mice in relationship with insulin resistance and impaired glucose tolerance. Rancoule al.Involvement of autotaxin/lysophosphatidic acid signaling in obesity and impaired glucose homeostasis.Biochimie. 2014 Jan;96:140-3
  • Black KE1, et al. Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis. FASEB J. 2016 Jun;30(6):2435-50.
  • Mouratis MA1,et al. Autotaxin and Endotoxin-Induced Acute Lung Injury. PLoS One. 2015 Jul 21;10(7):e0133619.
  • This review summarizes the recent findings on the relation between ATX or LPA and liver fibrosis, the usefulness of serum ATX levels to predict the stages of liver fibrosis, and speculated roles of increased serum ATX and plasma LPA levels in liver fibrosis. Ikeda H1, Yatomi Y.Autotaxin in liver fibrosis.Clin Chim Acta. 2012 Nov 20;413(23-24):1817-21.
  • Size: 96 T
    Standard Range: 0.5-32 ng/ml
    Sensitivity: 100 pg/ml
    Sample Type: serum, plasma
    Dilution Factor: 40 for plasma and serum
    Intra-CV: 4-6%
    Inter-CV: 8-12%
    Protocol: PDF

Autotaxin/ENPP2 (Rat/Mouse) ELISA Kit
Our Price: $460.00

Rat Mouse Autotaxin Enpp2

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